Product: | Asparaginase | ||||||
---|---|---|---|---|---|---|---|
Catalog Number: | 17357 | ||||||
CAS Number: | 9015-68-3 | ||||||
Synonyms: | L-Asparagine Amidohydrolase | ||||||
Pricing: |
|
||||||
Formula: | C1377H2208N382O442S17 | ||||||
Molecular Weight: | 295.35 | ||||||
Appearance: | Lyophilized powder | ||||||
Category: | Anti-cancer compounds | ||||||
Stability: | Stable under recommended storage conditions. | ||||||
Storage: |
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2-8°C. |
||||||
Transportation: |
Non-hazardous for transport |
||||||
Literature References: |
Amy L. Swain, Mariusz Jaskolski, Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy Proc. Natl. Acad. Sci. U. S. A., 1993, 90:1474-1478.; Michel Duval, Stefan Suciu, Comparison of Escherichia coli–asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer—Children’s Leukemia Group phase 3 trial Blood, 2002, 99, 2734-2739.; Mario Sanches, Structural comparison of Escherichia coli L-asparaginase in two monoclinic space groups, Acta Crystallogr. D, 2003, 59(3):416.; Merck 14,836 |
||||||
MSDS: | |||||||
Applications: |
Asparaginase is an enzyme used in the treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma in children. It has minimal bone marrow toxicity.2 |