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Product: Leuprolide Acetate
Catalog Number: 17541
CAS Number: 74381-53-6
Synonyms: Leuprolide Acetate salt;
des-Gly10-[D-Leu6]-LH-RH ethylamide
Pricing:
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Formula: C59H84N16O12 • xC2H4O2
Chemical Purity: >98%
Molecular Weight: 1209.40
Structure: Leuprolide Acetate
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Appearance: White powder
Category: Anti-cancer compounds
Stability: Stable under recommended storage conditions
Storage:

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Transportation:

Non-hazardous for transport

Literature References:

Zheng, Y, et al., Permeability and absorption of leuprolide from various intestinal regions in rabbits and rats. Int. J. Pharmacol. 185, 83, (1999); Goto, T., et al., Gonadotropin-releasing hormone agonist has the ability to induce increased matrix metalloproteinase (MMP)-2 and membrane type 1-MMP expression in corpora lutea, and structural luteolysis in rats. J. Endocrinol. 161, 393-402, (1999); Ogawa, T., et al., Leuprolide, a gonadotropin-releasing hormone agonist, enhances colonization after spermatogonial transplantation into mouse testes. Cell 30, 583-588, (1998); Ravivarapu, H.B., et al., Sustained suppression of pituitary-gonadal axis with an injectable, in situ forming implant of leuprolide acetate. J. Pharm. Sci. 89, 732-741, (2000); Imai, A., et al., Fas and Fas ligand system may mediate antiproliferative activity of gonadotropin-releasing hormone receptor in endometrial cancer cells. Int. J. Oncol. 13, 97-100, (1998); Merck 14,5457

Description:

Luteinizing hormone releasing hormone (LH-RH) agonist.

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