Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2-8°C.

IATA: Hazard Class: 6.1; UN Number: UN3462; Packing Group: III; Shipping Name: Toxins, extracted from living sources, solid, n.o.s. (Nigericin, monosodium salt)

S. Cafferel-Mendez, et. al. Reprod. Nutr. Dev. 27, 921, (1989); K. Suzuki, et. al. Anal. Chem. 60, 1714, (1988); Parfenova, H., et al., Phosphorylation-dependent stimulation of prostanoid synthesis by nigericin in cerebral endothelial cells. Am. J. Physiol. 277, C728-C738, (1999); Bevensee, M.O., et al., Effect of trace levels of nigericin on intracellular pH and acid-base transport in rat renal mesangial cells. J. Membr. Biol. 169, 131-139, (1999); Watanabe, N., et al., Activation of interleukin-1 β-converting enzyme by nigericin is independent of apoptosis. Cytokine 10, 645-653, (1998); Rey, B., et al., Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. BMC Physiol. 10, 5, (2010); Raben, N., et al., Monitoring Autophagy In Lysosomal Storage Disorders. Meth. Enzymol. 453, 417-49, (2009); Erdogan, S., et al., Changes In The Activity Of Defense Mechanisms Against Induced Acidosis During Meiotic Maturation In Mouse Oocytes. Theriogenology 75, 1057-66, (2011); Parfenova, H., et. al. Am. J. Physiol. 277, C728-C738, (1999); Bevensee, M.O., et. al. J. Membr. Biol. 169, 131-139, (1999); Watanabe, N., et. al. Cytokine 10, 645-653, (1998); Merck 14,6541; Beil. 19,V,12,550

Ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K⁺> Rb⁺≥ Cs⁺>> Na⁺. As ion-selective electrode - an efficient K⁺-carrier.^1,2