Inquire About a Product| Product: | Swainsonine | |
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| Catalog Number: | 17698 | |
| CAS Number: | 72741-87-8 | |
| Synonyms: | (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol | |
| Pricing: |
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| Formula: | C8H15NO3 | |
| Molecular Weight: | 173.21 | |
| Structure: |
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| Appearance: | Solid | |
| Category: | Anti-cancer compounds | |
| Stability: | Stable under recommended storage conditions. | |
| Storage: |
Keep container tightly closed in a dry and well ventilated place. Recommended storage temperature: -20°C |
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| Transportation: |
Non-hazardous for transport |
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| Literature References: |
Sim, K.L. and Perry, D., Analysis of swainsonine and its early metabolic precursors in cultures of Metarhizium anisopliae. Glycoconj. J. 14, 661, (1997); Elbein, A.D., Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains. Annu. Rev. Biochem. 56, 497, (1987); Fujieda, S., et al., Swainsonine augments the cytotoxicity of human lymphokine-activated killer cells against autologous thyroid cancer cells. Arch. Otolaryngol. Head Neck Surg. 120, 389, (1994); Beil. 21,V,5,480 |
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| MSDS: | ||
| Description: |
Swainsonine is a potent inhibitor of various α-mannosidases, especially of α-mannosidase II. It inhibits glycoprotein processing and also acts as immune modulator |