Inquire About a Product| Product: | Wogonin | ||||||||
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| Catalog Number: | 33775 | ||||||||
| CAS Number: | 632-85-9 | ||||||||
| Synonyms: | 5,7-dihydroxy-8-methoxy-2-phenylchromen-4-one | ||||||||
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| Formula: | C16H12O5 | ||||||||
| Chemical Purity: | 98% | ||||||||
| Molecular Weight: | 284.26 | ||||||||
| Structure: |
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| Category: | Heterocyclic Compounds | ||||||||
| Literature References: |
Hui KM, Huen MS, Wang HY, Zheng H, Sigel E, Baur R, Ren H, Li ZW, Wong JT, Xue H., Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochem. Pharmacol., 2002, 64 (9): 1415–24.; Lin CC, Kuo CL, Lee MH, Lai KC, Lin JP, Yang JS, Yu CS, Lu CC, Chiang JH, Chueh FS, Chung JG, Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. Int J Oncol, 2011, 39 (1): 217–224. |
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| MSDS: | |||||||||
| Description: | Phytochemical | ||||||||
| Applications: | An O-methylated flavone. May have anxiolytic properties. May also have anti-tumor properties and anticonvulsant effects. Acts as a positive allosteric modulator of the benzodiazepine site of the GABA-A receptor. |