Li, J., Hu, W., Baldassare, J.J., et al. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci,2003, 73 1083-1096.
The labeled neutral, more lipophilic form of linoleic acid. May contribute to ethanol-induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells. Increases cyclin E expression and Cdk2, ERK and JNK activity.