Inquire About a Product| Product: | Linoleic acid-9,10,12,13-d4 ethyl ester | ||||
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| Catalog Number: | D144 | ||||
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| Formula: | CH3(CH2)3(CH2CD=CD)2(CH2)7*COOCH2CH3 | ||||
| Enrichment: | 98%D | ||||
| C Chain: | C18:2 | ||||
| Double Bonds: | 9 cis, 12 cis | ||||
| Category: | Fatty Acids 13C & 2H Alphabetical Listing | ||||
| Literature References: |
Li, J., Hu, W., Baldassare, J.J., et al. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci, 2003, 73 1083-1096. |
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| MSDS: | |||||
| Applications: | The labeled neutral, more lipophilic form of linoleic acid. May contribute to ethanol-induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells. Increases cyclin E expression and Cdk2, ERK and JNK activity. |