Inquire About a Product| Product: | Lathosterol-2,2,4,4-d4 | ||||
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| Catalog Number: | D33670 | ||||
| Unlabeled CAS Number: | 80-99-9 | ||||
| Pricing: |
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| Formula: | C27H42D4O | ||||
| Enrichment: | 99 atom % D | ||||
| Molecular Weight: | 390.68 | ||||
| Structure: |
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| Category: | Labeled Steroids & Hormones | ||||
| Literature References: |
Kempen, H.J., Glatz, J.F., Leuven, J.A.G., van de Voort, H.A., Katan, M.B., Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. The Journal of Lipid Research, 1988, Sep., 29:1149-1155.; Krakowiak, P.A., et al., Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency. Hum. Mol. Genet., 2003, 12(13):1631-1641. |
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| MSDS: | |||||
| Applications: | The labeled direct precursor to cholesterol. By measuring the levels of lathosterol in a patients blood, the amount of cholesterol produced can be measured. Significantly elevated levels of lathosterol can identify patients with increased risk of premature coronary heart disease. |