Product: | L-Citrulline-2,3,3,4,4,5,5-d7 | ||||
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Catalog Number: | D5259 | ||||
CAS Number: | 2483831-24-7 | ||||
Synonyms: |
L-2-Amino-5-ureidovaleric acid; (S)-2-Amino-5-ureidopentanoic acid |
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Pricing: |
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Formula: | H2NCONH(CD2)3CD(NH2)COOH | ||||
Enrichment: | 98%D | ||||
Molecular Weight: | 182.23 | ||||
Structure: | |||||
Appearance: | White solid | ||||
Category: | Labeled Amino Acids and Derivatives | ||||
Literature References: |
Rogers, G. E.; Rothnagel, J. A., A sensitive assay for the enzyme activity in hair follicles and epidermis that catalyses the peptidyl-arginine-citrulline post-translational modification. Current problems in dermatology, 1983, 11: 171–184.; Coenen D, Verschueren P, Westhovens R, Bossuyt X., Technical and diagnostic performance of 6 assays for the measurement of citrullinated protein/peptide antibodies in the diagnosis of rheumatoid arthritis. Clin. Chem., 2007, 53 (3): 498–504. |
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MSDS: | |||||
Applications: | A labeled alpha-amino acid. A key intermediate in the urea cycle. A byproduct of the production of nitric oxide. Patients with rheumatoid arthritis have antibodies against proteins containing citrulline. Used as a biomarker of intestinal functionality. |