Product: | (RS)-S-Adenosyl-L-methionine-d3 tetra(p-toluenesulfonate) salt | ||||
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Catalog Number: | D998 | ||||
Unlabeled CAS Number: | 17176-17-9 | ||||
Synonyms: |
Adenosine-5-methionine-d3 p-Toluenesulfonate; Ademetionine-d3 |
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Pricing: |
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Formula: | C15H19D3N6O5S • 4 C7H8O3S | ||||
Molecular Weight: | 1089.24 | ||||
Structure: | |||||
Appearance: | White solid | ||||
Category: | Nucleic Acids - 13C, 15N Alphabetical Listing | ||||
Stability: | Stable under recommended storage conditions. | ||||
Storage: |
KEEP FROZEN. Adequate ventilation. Protect from moisture |
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Transportation: |
Non-hazardous for transport |
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Literature References: |
Bressa, GM, S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994, 154: 7–14.; Cantoni, GL, The Nature of the Active Methyl Donor Formed Enzymatically from L-Methionine and Adenosinetriphosphate. J Am Chem Soc, 1952, 74 (11): 2942–3.; Kagan, BL; Sultzer, DL; Rosenlicht, N; Gerner, RH, Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry, 1990, May 147 (5): 591–5.; Papakostas, GI, Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr., 2002, Nov., 76(5): 1158S–61S.; Rosenbaum, JF; Fava, M; Falk, WE; Pollack, MH; Cohen, LS; Cohen, BM; Zubenko, GS, The antidepressant potential of oral S-adenosyl-l-methionine. Acta Psychiatrica Scandinavica, 1990, May, 81 (5): 432–6. |
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MSDS: | |||||
Applications: | Labeled compound. Used in the US as a nutritional supplement. Studies have shown if taken on a regular basis, the compound may help fight depression, liver disease, and the pain of osteoarthritis. Transmethylation, transsulfuration and aminopropylation are the metabolic pathways that require S-adenosyl methionine. |