Inquire About a Product| Product: | Tacrolimus | ||||
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| Catalog Number: | 10248 | ||||
| CAS Number: | 104987-11-3 | ||||
| Synonyms: | Advagraf; FR 900506; Fujimycin; L 679934; Prograf; Protopic; TacroBell; FK-506; Tsukubaenolide | ||||
| Pricing: |
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| Formula: | C44H69NO12 | ||||
| Molecular Weight: | 804.02 | ||||
| Structure: |
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| Appearance: | White to Off-White Solid | ||||
| Category: | Unlabeled Reference Standards | ||||
| Stability: | Stable under recommended storage conditions. | ||||
| Storage: |
Long term -20°C Freezer |
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| Transportation: |
Non-hazardous for transport |
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| Literature References: |
Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999), |
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| MSDS: | |||||
| Applications: |
An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+ |