Product: Alverine Citrate
Catalog Number: 16279
CAS Number: 5560-59-8
Synonyms: N-Ethyl-3,3´-diphenlyldipropylamine;
Alverine citrate salt
Pricing:
5 g =  $585   (In Stock) Add to Cart
25 g =  $900   (In Stock) Add to Cart
Formula: C20H27N • C6H8O7
Molecular Weight: 473.56
Structure: Alverine Citrate
Appearance: Solid
Category: Biochemicals and Reagents
Stability: Stable under recommended storage conditions
Storage:

Keep container tightly closed in a dry and well-ventilated place

Transportation:

Non-hazardous for transport

Literature References:

G. Jansen, et al., Chemogenomic profiling predicts antifungal synergies Mol. Syst. Biol. 5, (2009); T. Wittmann, et al., Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomport in irritable bowel syndrome - a randomized, double-blind, placebo-controlled study Aliment. Pharmacol. Ther. 31, 615-624, (2010); V. M. Gohil, et al., Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis Nat. Biotechnol. 28, 249-255, (2010); A. F. Fliri, et al., Drug Effects Viewed from a Signal Transduction Network Perspective J. Med. Chem. 52, 8038-8046, (2009); D. Ju, et al., Dyclonine and alverine citrate enhance the cytotoxic effects of proteasome inhibitor MG132 on breast cancer cells Int. J. Mol. Med. 23, 205-209, (2009); M. Hayase, et al., Evolving mechanisms of action of alverine citrate on phasic smooth muscles Br. J. Pharmacol. 152, 1228-1238, (2007); Merck 14,371

MSDS:
Applications:

Used for studies of pharmacological activity including:
• Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
• Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
• Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
• Drug effects viewed from a signal transduction network perspective
• Enhanced cytotoxic effect of proteasome inhibitor MG132
• Mechanism of action on phasic smooth muscles