Inquire About a Product| Product: | Calcium Folinate | ||||||
|---|---|---|---|---|---|---|---|
| Catalog Number: | 17397 | ||||||
| CAS Number: | 6035-45-6 | ||||||
| Synonyms: |
Folinic acid calcium salt hydrate; 5-Fromyl-5,6,7,8-tetrahydropteroyl-L-glutamic; Leucovorincalcium salt; 5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt; Citrovorum factorcalcium salt |
||||||
| Pricing: |
|
||||||
| Formula: | C20H21CaN7O7 • xH2O | ||||||
| Chemical Purity: | >99% | ||||||
| Molecular Weight: | 511.50 | ||||||
| Structure: |
|
||||||
| Appearance: | Solid | ||||||
| Category: | Anti-cancer compounds | ||||||
| Stability: | Stable under recommended storage conditions. | ||||||
| Storage: |
Keep container tightly closed in a dry and well-ventilated place. Hygroscopic, store under inert gas. Light and air sensitive. |
||||||
| Transportation: |
Non-hazardous for transport |
||||||
| Literature References: |
L.O. Pont et al. Anal. Profiles Drug Subst. 8, 315, (1979) |
||||||
| MSDS: | |||||||
| Description: |
Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer. |