Inquire About a Product| Product: | Ilmofosine | ||||
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| Catalog Number: | 17520 | ||||
| CAS Number: | 83519-04-4 | ||||
| Synonyms: |
1-Hexadecylmercapto-2-methoxymethyl-3-propyl phosphoric acid monocholine ester; BM 41.440 |
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| Pricing: |
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| Formula: | C26H56NO5PS | ||||
| Molecular Weight: | 525.77 | ||||
| Structure: |
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| Appearance: | Wax like | ||||
| Category: | Anti-cancer compounds | ||||
| Stability: | Stable under recommended storage conditions | ||||
| Storage: |
Keep container tightly closed in a dry and well ventilated place. Recommended storage temperature: -20°C. Air sensitive |
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| Transportation: |
IATA: Hazard Class: 6.1; UN Number: UN2811; Packing Group: III; Shipping Name: Toxic solid, organic, n.o.s. (Ilmofosine) |
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| Literature References: |
Goekjian P. G, Jirousek M. R,., Protein kinase C inhibitors as novel anticancer drugs. Expert Opin. Investig. Drugs 10, 2117-2140, (2001) |
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| MSDS: | |||||
| Description: |
Protein Kinase C (PKC) inhibitor; an ether lipid derivative of lysophosphatidylcholine has antineoplastic activity in vitro and in vivo. IC50 = 560 nM. Competitive at the regulatory site of PKC. Ilmofosine is active against a variety of explanted human non-small cell lung, breast, colorectal, ovarian, renal cell cancer, and melanoma tumors in vitro at concentrations of 1-30 μg/mL. |