Inquire About a Product| Product: | Mecamylamine HCl | ||||||||
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| Catalog Number: | 5476 | ||||||||
| CAS Number: | 826-39-1 | ||||||||
| Synonyms: | 2-(Methylamino)isocamphane hydrochloride; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride; Inversine | ||||||||
| Pricing: |
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| Formula: | C11H21N • HCl | ||||||||
| Molecular Weight: | 203.75 | ||||||||
| Structure: |
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| Appearance: | Solid | ||||||||
| Category: | Unlabeled Reference Standards | ||||||||
| Stability: | Stable under recommended storage conditions | ||||||||
| Storage: |
Keep container tightly closed in a dry and well ventilated place |
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| Transportation: |
IATA: Hazard Class: 6.1; UN Number: UN2811; Packing Group: III; Shipping Name: Toxic solid, organic, n.o.s. (Mecamylamine hydrochloride) |
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| Literature References: |
Castillo, P.E., et al., Multiple and opposing roles of cholinergic transmission in the main olfactory bulb. J. Neurosci. 19, 9180-9191, (1999); Damaj, M.I., et al., Pharmacological characterization of nicotine-induced seizures in mice. J. Pharmacol. Exp. Ther. 291, 1284-1291, (1999); Panagis, G., et al., Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Synapse 35, 15-25, (2000); Al-Zi'abi, M.O., et al., Survival Role Of Locally Produced Acetylcholine In The Bovine Corpus Luteum. Biol. Reprod. 80, 823-32, (2009); Merck 14,5774 |
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| MSDS: | |||||||||
| Description: |
Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier |