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|Category:||Labeled Amino Acids and Derivatives|
Radwanski ER, Last RL, Tryptophan biosynthesis and metabolism: biochemical and molecular genetics. The Plant Cell, 1995 Jul, 7(7): 921–34.; Schaechter JD, Wurtman RJ. Serotonin release varies with brain tryptophan levels. Brain Research, 1990 Nov, 532(1-2): 203–10.; Ravindran AV, da Silva TL, Complementary and alternative therapies as add-on to pharmacotherapy for mood and anxiety disorders: a systematic review. Journal of Affective Disorders, 2013 Sep, 150(3): 707–19.
|Applications:||A labeled essential amino acid. Acts as a building block in protein synthesis. A precursor for serotonin, niacin, and auxin. Activates a repressor protein in bacteria that binds to the trp operon, which prevents transcription of downstream DNA coding for the synthesis of tryptophan. Found in a wide variety of food sources. May improve depression symptoms.|