Product: Linoleic Acid-9,10,12,13-d4 Ethyl Ester
Catalog Number: D144
5 mg =  $750   (In Stock) Add to Cart
Formula: CH3(CH2)3(CH2CD=CD)2(CH2)7*COOCH2CH3
Enrichment: 98%D
C Chain: C18:2
Double Bonds: 9 cis, 12 cis
Category: Fatty Acids 13C & 2H Alphabetical Listing
Literature References:

Li, J., Hu, W., Baldassare, J.J., et al. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci, 2003, 73 1083-1096.

Applications: The labeled neutral, more lipophilic form of linoleic acid. May contribute to ethanol-induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells. Increases cyclin E expression and Cdk2, ERK and JNK activity.