Product: | 7a-Hydroxy-4-cholesten-3-one | ||||
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Catalog Number: | 10704 | ||||
CAS Number: | 3862-25-7 | ||||
Synonyms: |
(7a)-7-Hydroxycholest-4-en-3-one; 7a-Hydroxycholest-4-en-3-one |
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Pricing: |
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Formula: | C27H44O2 | ||||
Chemical Purity: | 98% | ||||
Molecular Weight: | 400.64 | ||||
Structure: | |||||
Appearance: | White solid | ||||
Category: | Metabolites and Impurities | ||||
Stability: | Stable under recommended storage conditions. | ||||
Storage: |
Keep container closed, keep away from heat and open flame, store under nitrogen, refrigerate |
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Transportation: |
Non-hazardous for transport |
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Literature References: |
Gälman, C; Angelin, B; Rudling, M., Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis. Gastroenterology, 2005, 129 (5): 1445–53.; Russell, DW, The enzymes, regulation, and genetics of bile acid synthesis. Annual review of biochemistry, 2003, 72: 137–74.; Brydon, WG; Nyhlin, H; Eastwood, MA; Merrick, MV, Serum 7 &α;-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea. European journal of gastroenterology & hepatology, 1996, 8 (2): 117–23. |
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MSDS: | |||||
Description: | An intermediate in the synthesis of bile acids from cholesterol. Serum concentrations reflect the activity of bile acid synthetic pathway. Elevated values suggest bile acid malabsorption. |