Inquire About a Product| Product: | KN-62 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number: | 11303 | ||||||||
| CAS Number: | 127191-97-3 | ||||||||
| Synonyms: |
(S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester; 1-[N,O-bis(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine |
||||||||
| Pricing: |
|
||||||||
| Formula: | C38H35O6S2 | ||||||||
| Chemical Purity: | >95% | ||||||||
| Molecular Weight: | 721.84 | ||||||||
| Structure: |
|
||||||||
| Appearance: | White powder | ||||||||
| Category: | Protein Kinase Inhibitors and Activators | ||||||||
| Stability: | Stable under recommended storage conditions. | ||||||||
| Storage: |
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. |
||||||||
| Transportation: |
Non-hazardous for transport |
||||||||
| Literature References: |
MacLeod, et al., Ca(2+)/Calmodulin kinase II and decreases in intracellular pH are required to activate K(+) channels after substantial swelling in villus epithelial cells. J. Membr. Biol. 172, 59-66, (1999); Fan, et al., Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence. Mol. Pharmacol. 56, 39-45, (1999); Communi, et al., Calcium-calmodulin-dependent protein kinase II and protein kinase C-mediated phosphorylation and activation of D-myo-inositol 145-trisphosphate 3-kinase B in astrocytes. J. Biol. Chem. 274, 14734-14742, (1999) |
||||||||
| MSDS: | |||||||||
| Description: |
Selectively inhibits rat brain Ca2+/calmodulin-dependent protein kinase II. |