Product: D-erythro-Sphingosine-1-Phosphate
Catalog Number: 13515
CAS Number: 26993-30-6
Synonyms: Sphingosine 1-phosphate
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Formula: C18H38NO5P
Chemical Purity: >95%
Molecular Weight: 379.47
Structure: D-erythro-Sphingosine-1-Phosphate
Appearance: Powder
Category: Chemical Activators
Stability: Stable under recommended storage conditions.

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.


Non-hazardous for transport

Literature References:

Byfield, F.J., et al., Cathelicidin LL-37 Peptide Regulates Endothelial Cell Stiffness And Endothelial Barrier Permeability. Am. J. Physiol. Cell Physiol. 300, C105-12, (2011); Panetti, T.S., Differential effects of sphingosine 1-phosphate and lysophosphatidic acid on endothelial cells. Biochim. Biophys. Acta 1582, 190-196, (2002); Mattie, M., et al., Sphingosine-1-phosphate: a putative second messenger mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J. Biol. Chem. 269, 3181, (1994)


A lipid second messenger that binds to S1P1 and S1P3 receptors. Mobilizes intracellular Ca2+ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis