Product: Neomycin Sulfate
Catalog Number: 17851
CAS Number: 1405-10-3
Synonyms: Neomycin trisulfate salt hydrate
5 mg =  Inquire  
50 mg =  Inquire  
Formula: C23H46N6O13 • 3H2SO4 • xH2O
Molecular Weight: 908.88
Structure: Neomycin Sulfate
Appearance: Powder
Category: Antibiotics
Stability: Stable under recommended storage conditions.

Keep container tightly closed in a dry and well-ventilated place


Non-hazardous for transport

Literature References:

Panda, S.K., Broitman, S.A., Fecal excretion pattern of bile acids in rats fed high fat diets and neomycin in induced colon tumorigenesis. Bioorg. Med. Chem. Lett. 9, 2459, (1999); Huang, Y., et al., Effects of phosphatidylinositol 4,5-bisphosphate and neomycin on phospholipase D: kinetic studies. Mol. Cell Biochem. 197, 195, (1999); Kim, K.T., et al., Neomycin inhibits catecholamine secretion by blocking nicotinic acetylcholine receptors in bovine adrenal chromaffin cells. J. Pharmacol. Exp. Ther. 288, 73, (1999); Teupser, D., et al., Novel Strategy Using F1-congenic Mice For Validation Of QTLs: Studies At The Proximal Chromosome 10 Atherosclerosis Susceptibility Locus. Arterioscler. Thromb. Vasc. Biol. 29, 678-83, (2009); Lu, J., et al., Dynamic Ensemble View Of The Conformational Landscape Of HIV-1 TAR RNA And Allosteric Recognition. Biochemistry 50, 5042-57, (2011); Merck 14,6454


Blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons. Mode of action: binds to the 30S and in some cases the 50S subunit causing miscoding; inhibits initiation and elongation during protein synthesis. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria


Used in molecular biology as a selection agent for prokaryotic cells that have been transformed using the selectable marker gene (neo).