Product: Streptomycin Sulfate Sterile
Catalog Number: 17862
CAS Number: 3810-74-0
5 mg =  Inquire  
50 mg =  Inquire  
Formula: C21H39N7O12 • 1.5H2O4S
Molecular Weight: 728.69
Structure: Streptomycin Sulfate Sterile
Appearance: Powder
Category: Antibiotics
Stability: Stable under recommended storage conditions.

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2-8°C.


Non-hazardous for transport

Literature References:

Merck 14,8826; Beil. 18,V,11,82


Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation.
Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates.


Recommended for use in embryo culture at 50 mg/L. Stock solutions should be sterile-filtered and stored at 2-8 °C for up to a month or at -20 °C for extended periods. Solutions are stable at 37 °C for 3 days. Use to inhibit bacterial protein synthesis at the level of initiation. Use to study mechanisms of streptomycin resistance. Use together with penicillin and other agents to inhibit bacterial contamination in cell culture applications.