Product: Mecamylamine HCl
Catalog Number: 5476
CAS Number: 826-39-1
Synonyms: 2-(Methylamino)isocamphane hydrochloride; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride; Inversine
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Formula: C11H21N • HCl
Molecular Weight: 203.75
Structure: Mecamylamine HCl
Appearance: Solid
Category: Unlabeled Reference Standards
Stability: Stable under recommended storage conditions

Keep container tightly closed in a dry and well ventilated place


IATA: Hazard Class: 6.1; UN Number: UN2811; Packing Group: III; Shipping Name: Toxic solid, organic, n.o.s. (Mecamylamine hydrochloride)

Literature References:

Castillo, P.E., et al., Multiple and opposing roles of cholinergic transmission in the main olfactory bulb. J. Neurosci. 19, 9180-9191, (1999); Damaj, M.I., et al., Pharmacological characterization of nicotine-induced seizures in mice. J. Pharmacol. Exp. Ther. 291, 1284-1291, (1999); Panagis, G., et al., Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Synapse 35, 15-25, (2000); Al-Zi'abi, M.O., et al., Survival Role Of Locally Produced Acetylcholine In The Bovine Corpus Luteum. Biol. Reprod. 80, 823-32, (2009); Merck 14,5774


Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier