Inquire About a Product| Product: | 24(S)-Hydroxycholesterol | ||||
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| Catalog Number: | 731 | ||||
| CAS Number: | 474-73-7 | ||||
| Pricing: |
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| Formula: | C27H46O2 | ||||
| Chemical Purity: | 98% | ||||
| Molecular Weight: | 402.7 | ||||
| Structure: |
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| Category: | Cholesterol | ||||
| Stability: | Stable | ||||
| Storage: |
Keep tightly closed |
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| Transportation: |
Non-hazardous for transport |
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| Literature References: |
Bjorkhem, I., Lutjohann, D., Breuer, O., Sakinis, A., Wennmalm, A., Importance of a Novel Oxidative Mechanism for Elimination of Brain Cholesterol Turnover of Cholesterol and 24(S)-Hydroxycholesterol in Rat Brain as Measured with 18O2Techniques in vivo and in vitro. The Journal of Biological Chemistry, 1997, Nov., 272:30178-30184.; Kolsch, H., Lutjohann, D., Tulke, A., Bjorkhem, A., Rao, M.L., The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells. Brain Research, 1999, Feb., 818(1):171-175. |
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| MSDS: | |||||
| Applications: | A labeled derivative of cholesterol. Synthesized exclusively in the brain. Possesses the ability to cross the blood-brain barrier. Maintains brain cholesterol homeostasis. Precursor to bile acids. Correlation between increased levels of the compound and the occurrence of active demyelinating diseases such as Alzheimer's disease. |