Product: | Entecavir Monohydrate | ||||
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Catalog Number: | 9858 | ||||
CAS Number: | 142217-69-4 | ||||
Synonyms: |
2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one; Baraclude; BMS 200475; SQ 34676 |
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Pricing: |
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Formula: | C12H15N5O3 | ||||
Molecular Weight: | 277.28 | ||||
Structure: | |||||
Appearance: | White crystalline powder | ||||
Category: | Nucleotides and Nucleosides Alphabetic Listing | ||||
Stability: | Stable under recommended storage conditions. | ||||
Storage: |
Glass, polyethylene or polypropylene container. Check all containers are clearly labeled and free from leaks. Keep containers securely sealed |
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Literature References: |
Thomas, H., et al. 2003. J. Hepatol. 39: S93-S98. PMID: 14708685; Rivkin, A. 2007. Drugs Today. 43: 201-220. PMID: 17460784 |
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MSDS: | |||||
Description: |
Entecavir is a deoxyguanosine nucleoside analogue with antiviral activity against the hepatitis B virus (HBV). The compound has a mechanism of action by inhibiting priming and chain extension through inhibition of HBV DNA polymerase. Entecavir is also documented as the most potent HBV DNA polymerase inhibitor and superior to Lamivudine due to its effectiveness against Lamivudine resistant HBV |