Inquire About a Product| Product: | (S)-Equol | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number: | 9885 | ||||||||
| CAS Number: | 531-95-3 | ||||||||
| Synonyms: |
(S)-3-(4-Hydroxy-phenyl)-chroman-7-ol; (S)-3,4-Dihydro-3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol; 3-(4-Hydroxy-phenyl)-chroman-7-ol |
||||||||
| Pricing: |
|
||||||||
| Formula: | C15H14O3 | ||||||||
| Chemical Purity: | >98% | ||||||||
| Molecular Weight: | 242.27 | ||||||||
| Structure: |
|
||||||||
| Appearance: | Crystalline solid | ||||||||
| Category: | Chiral Reagents Alphabetic Listing | ||||||||
| Stability: | Stable under recommended storage conditions. | ||||||||
| Storage: |
Polyethylene or polypropylene container. Check all containers are clearly labeled and free from leaks. Keep containers securely sealed. No smoking, naked lights or ignition sources. Store in a cool, dry, well-ventilated area. Check regularly for leaks |
||||||||
| Transportation: |
Non-hazardous for transport |
||||||||
| Literature References: |
Lund, T.D., et al. 2004. Biol. Reprod. 70: 1188-1195. PMID: 14681200 |
||||||||
| MSDS: | |||||||||
| Description: |
Equol is a non-steroidal estrogen. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). Also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies |