Product: Hydroxy Itraconazole-d8
Catalog Number: D10837
CAS Number: 1217516-26-1
Synonyms: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl-d8)-3H-1,2,4-triazol-3-one;
R 63373-d8
1 mg =  $590   Add to Cart
Formula: C35H30D8Cl2N8O5
Molecular Weight: 729.68
Structure: Hydroxy Itraconazole-d<sub>8</sub>
Category: Antibiotics
Literature References:

Odds, F.C., Bossche, H.V., Antifungal activity of itraconazole compared with hydroxy-itraconazole in vitro. J. Antimicrob. Chemother., 2000, 45(3):371-373.; Hennig, S., Wainwright, C.E., Bell, S.C., Miller, H., Friberg, L.E., Charles, B.G., Population Pharmacokinetics of Itraconazole and its Active Metabolite Hydroxy-Itraconazole in Paediatric Cystic Fibrosis and Bone Marrow Transplant Patients. Clinical Pharmacokinetics, 2006, 45(11):1099-1114.

Applications: Labeled metabolite of itraconazole, formed in the liver. Used as an antimycotic.