Product: | 7β-Hydroxycholesterol-25,26,26,26,27,27,27-d7 | ||||
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Catalog Number: | D181 | ||||
CAS Number: | 349553-97-5 | ||||
Pricing: |
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Formula: | C27H39D7O2 | ||||
Enrichment: | 98%D | ||||
Molecular Weight: | 409.70 | ||||
Structure: |
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Category: | Cholesterol | ||||
Literature References: |
Spyridopoulos, et al., Alcohol enhances oxysterol-induced apoptosis in human endothelial cells by a calcium-dependent mechanism. Arteriosclerosis, Thrombosis, and Vascular Biology, 2001, 21(3):439-444.; Lizard, G., et al. Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall. Arteriosclerosis, Thrombosis, and Vascular Biology, 1999, 19(5):1190-1200. |
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MSDS: | |||||
Applications: | A labeled oxysterol. A precursor to bile acids. A product of cholesterol oxidation. Cytotoxic, induces cell death in monocytes, smooth muscle cells, and endothelial cells. Increased levels correlates with increased risk of cardiovascular diseases. |