Product: 7β-Hydroxycholesterol-25,26,26,26,27,27,27-d7
Catalog Number: D181
CAS Number: 349553-97-5
1 mg =  $390   (In Stock) Add to Cart
Formula: C27H39D7O2
Enrichment: 98%D
Molecular Weight: 409.70
Structure: 7β-Hydroxycholesterol-25,26,26,26,27,27,27-d<sub>7</sub>
Category: Cholesterol
Literature References:

Spyridopoulos, et al., Alcohol enhances oxysterol-induced apoptosis in human endothelial cells by a calcium-dependent mechanism. Arteriosclerosis, Thrombosis, and Vascular Biology, 2001, 21(3):439-444.; Lizard, G., et al. Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall. Arteriosclerosis, Thrombosis, and Vascular Biology, 1999, 19(5):1190-1200.

Applications: A labeled oxysterol. A precursor to bile acids. A product of cholesterol oxidation. Cytotoxic, induces cell death in monocytes, smooth muscle cells, and endothelial cells. Increased levels correlates with increased risk of cardiovascular diseases.