Product: 2,3-Pyridinedicarboxylic acid-d3
Catalog Number: D18880
Unlabeled CAS Number: 89-00-9
CAS Number: 138946-42-6
Synonyms: Quinolinic Acid-d3
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Formula: C7H2D3NO4
Molecular Weight: 170.14
Structure: 2,3-Pyridinedicarboxylic acid-d<sub>3</sub>
Category: Heterocyclic Compounds
Literature References:

Guillemin, Gilles J., Quinolinic acid: neurotoxicity. FEBS Journal, 2012, March, 279(8): 1355.; Guillemin, Giles, Quinolinic acid, the inescapable neurotoxin. FEBS Journal, 2012, April, 279 (8): 1356–1365.; Tan, Lin; Yu, JT; Tan, L., The kynurenine pathway in neurodegenerative diseases: Mechanistic and therapeutic considerations. Journal of the Neurological Sciences, 2012, Dec., 323 (1–2): 1–8.

Applications: A labeled NMDA receptor agonist. Inhibits glucose synthesis. Has potent neurotoxic effects. May be involved in many psychiatric disorders. Increased levels in the brain may contribute to apoptosis of astrocytes and neurons.