Product: Rapamycin-16-d3
Catalog Number: D3296
Unlabeled CAS Number: 53123-88-9
CAS Number: 392711-19-2
Synonyms: Sirolimus-d3, (-)-Rapamycin-d3; AY 22989-d3; Antibiotic AY 22989-d3; Cypher-d3; NSC 226080-d3; RAPA-d3;;
RPM-d3; Rapammune-d3; Rapamune-d3; SIIA 9268A-d3; Sirolimus-d3; Wy 090217-d3
1 mg =  $590   Add to Cart
Formula: C51H76D3NO13
Molecular Weight: 917.19
Structure: Rapamycin-16-d<sub>3</sub>
Category: Labeled Reference Standards
Stability: Stable under recommended storage conditions.

-20°C Freezer, Under Inert Atmosphere, temperature and moisture sensitive


Non-hazardous for transport

Literature References:

McAlister VC, Mahalati K, Peltekian KM, Fraser A, MacDonald AS., A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration.Ther Drug Monit., 2002, June, 24(3): 346–50.; Morelon E, Stern M, Israël-Biet D et al., Characteristics of sirolimus-associated interstitial pneumonitis in renal transplant patients. Transplantation, 2001, Sep., 72 (5): 787–90.

Applications: A labeled immunosuppressant and antiproliferative. May be useful in the treatment of some cancers. Prevents the activation of T and B cells. Used to prevent rejection from organ transplantation. Used with coronary stents to prevent restenosis in coronary arteries.