Product: Desmosine-d4 inner salt
Catalog Number: D5724
Unlabeled CAS Number: 11003-57-9
Notes:

Hygroscopic, contains water. See COA
Pricing:
1 mg =  $690   Add to Cart
Enrichment: d0 = 0.02%, d1 = 0.25%, d2 = 5.19%, d3 = 26.11%, d4 = 65.55%, d5
Chemical Purity: >95%
Category: Reference Standards for Inborn Errors
Literature References:

Cocci, F., et al., Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease Int. J. Biochem. Cell Biol. 2002, 34:594-604; Cantor, J.O., et al., Measurement of cross-linked elastin synthesis in bleomycin-induced pulmonary fibrosis using a highly sensitive assay for desmosine and isodesmosine J. Lab. Clin. Med., 1984, 103:384-392; Mecham, R.P., and Foster, J.A., A structural model for desmosine cross-linked peptides Biochem. J., 1978, 103:617-625.; Basalyga DM., et al., Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases. Circulation, 2004, 110:3480-3487.; Bailey M., et al., Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification. Am. J. Pathol., 2001, 159:1981-1986.; Starcher, B.C. and Galione, M.J. Prep. Biochem. 1975, 5:455.
MSDS:
Applications: Labeled desmosine. Desmosine concentrations can be measured in urine, plasma, and sputum samples as a marker for elastin breakdown, which can be linked to certain diseases.