Product: | Cyclosporin A-d4 | ||||
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Catalog Number: | D8710 | ||||
Unlabeled CAS Number: | 59865-13-3 | ||||
Synonyms: |
Cyclosporine-d4; Ciclosporin-d4; Atopica-d4; Sandimmun(e)-d4; Neoral-d4; Optimmune-d4 |
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Pricing: |
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Formula: | C62H107D4N11O12 | ||||
Molecular Weight: | 1206.64 | ||||
Structure: | |||||
Appearance: | White solid | ||||
Category: | Labeled Reference Standards | ||||
Stability: | Stable under recommended storage conditions | ||||
Storage: |
Keep container tightly closed in a dry and well-ventilated place. Store at -20°C |
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Transportation: |
Non-hazardous for transport. |
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Literature References: |
Cantrell DA, Smith KA, The interleukin-2 T-cell system: a new cell growth model. Science, 1984, 224 (4655): 1312–1316.; Lichtiger S, Present DH, Kornbluth A et al., Cyclosporine in severe ulcerative colitis refractory to steroid therapy. N. Engl. J. Med., 1994, 330 (26): 1841–5.; Naesens M, Kuypers DR, Sarwal M., Calcineurin inhibitor nephrotoxicity. Clin. J. Am. Soc. Nephrol., 2009, 4 (2): 481–509. |
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MSDS: | |||||
Applications: | A labeled immunosuppressant. Used in organ transplants to prevent rejection. Interferes with the activity and growth of T cells. Also used as a treatment for rheumatoid arthritis and psoriasis, as an opthalmic emulsion to treat dry eyes, and for persistent nummular keratitis among many other diseases. |