Product: | 25-Hydroxy cholesterol-26,26,26,27,27,27-d6 | ||||||||
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Catalog Number: | D17191 | ||||||||
CAS Number: | 88247-69-2 | ||||||||
Synonyms: | 5-Cholesten-3β,25-diol-26,26,26,27,27,27-d6 | ||||||||
Pricing: |
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Formula: | C27H40D6O2 | ||||||||
Enrichment: | 99 atom % d6 | ||||||||
Chemical Purity: | >99% | ||||||||
Molecular Weight: | 408.69 | ||||||||
Structure: | |||||||||
Appearance: | White solid | ||||||||
Category: | Cholesterol | ||||||||
Stability: | Stable under recommended storage conditions. | ||||||||
Storage: |
Store at 2 - 8 deg. C |
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Transportation: |
Non-hazardous for transport |
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Literature References: |
Adams, C.M., Reits, J., De Brabander, J.K., Feramisco, J.D., Li, L., Brown, M.S., Goldstein, J.L., Cholesterol and 25-hydroxycholesterol Inhibit Activation of SREBPs by Different Mecanisms, Both Involving SCAP and Insigs. J. Biol. Chem., 2004, 279(50):52772-52780. |
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MSDS: | |||||||||
Description: | 25-hydroxy Cholesterol contains six deuterium atoms at the 26, 26, 26, 27, 27, and 27 positions. It is intended for use as an internal standard for the quantification of 25-hydroxy cholesterol by GC- or LC-mass spectrometry. | ||||||||
Applications: | A labeled cholesterol derivative. Inhibits cholesterol synthesis. Suppresses the cleavage of sterol regulatory element binding proteins (SREBPs) in various cell types. Induces apoptosis. |