Product: | Tauroursodeoxycholic-2,2,3,4,4-d5 acid | ||||||||
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Catalog Number: | D31068 | ||||||||
Synonyms: |
2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic-d5 Acid; 3α,7β-Dihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)amide-d5; Ursodeoxycholyltaurine-d5 |
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Formula: | C26H40D5NO6S | ||||||||
Enrichment: | 97.8% | ||||||||
Chemical Purity: | 98% | ||||||||
Molecular Weight: | 504.73 | ||||||||
Structure: | |||||||||
Category: | Bile Acids | ||||||||
Literature References: |
Duan, WJ, Zhang, FK, Ou XJ, Zhang, T, Wang, XM, Wang, Y, Cui, Y, Zhao, XY, Jia, JD, The clinical profiles of primary biliary cirrhosis with a suboptimal biochemical response to ursodeoxycholic acid. Zhonghua Gan Zang Bing Za Zhi, 2011, 19 (2): 118–120.; Rivard, Andrew L, Steer, Clifford J, Kren, Betsey T, Rodrigues, Cecilia M.P, Castro, Rui E, Bianco, Richard W, Low, Walter C., Administration of Tauroursodeoxycholic Acid (TUDCA) Reduces Apoptosis Following Myocardial Infarction in Rat. The American Journal of Chinese Medicine, 2007, 35 (2): 279–295. |
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Applications: | A labeled ambiphilic bile acid. A taurine conjugate of ursodeoxycholic acid. Found in large quatities in bear bile. Only trace amounts found in humans. Used to treat gallstones and liver cirrhosis. Used in the US as a treatment for biliary cirrhosis. Has diminishing apoptotic effects, helps with cardiac function, Huntington's disease, Parkinson's disease, and stroke. Also has protective effects in the eye. |