Product: Everolimus
Catalog Number: 10192
CAS Number: 159351-69-6
Synonyms: 42-O-(2-Hydroxyethyl)rapamycin;
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Formula: C53H83NO14
Chemical Purity: 99.6%
Molecular Weight: 958.22
Structure: Everolimus
Appearance: White to faintly yellow powder
Category: All Inhibitors
Stability: Stable under recommended storage conditions.

Recommended storage temperature: -15 °C, in dry environment, protected from light.


Non-hazardous for transport

Literature References:

Motzer, R.J., Escudier, B., Oudard, S., Hutson, T.E., Porta, C., Bracarda, S., Grunwald, V., Thompson, J.A., FIglin, R.A., Hollaender, N., Urbanowitz, G., Berg, W.J., Kay, A., Lebwohl, D., Ravaud, A., Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. The Lancet, 2008, 372(9637):449-456.; Yao, J.C., et al., Everolimus for Advanced Pancreatic Neuroendocrine Tumors. The New England Journal of Medicine, 2011, 364:514-523.

Applications: An inhibitor of mammalian target of rapamycin. Used as an immunosuppressant to prevent organ transplant rejection. Also used as a treatment of renal cell cancer and other tumors.