Product: KN-62
Catalog Number: 11303
CAS Number: 127191-97-3
Synonyms: (S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester;
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Formula: C38H35O6S2
Chemical Purity: >95%
Molecular Weight: 721.84
Structure: KN-62
Appearance: White powder
Category: Protein Kinase Inhibitors and Activators
Stability: Stable under recommended storage conditions.

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.


Non-hazardous for transport

Literature References:

MacLeod, et al., Ca(2+)/Calmodulin kinase II and decreases in intracellular pH are required to activate K(+) channels after substantial swelling in villus epithelial cells. J. Membr. Biol. 172, 59-66, (1999); Fan, et al., Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence. Mol. Pharmacol. 56, 39-45, (1999); Communi, et al., Calcium-calmodulin-dependent protein kinase II and protein kinase C-mediated phosphorylation and activation of D-myo-inositol 145-trisphosphate 3-kinase B in astrocytes. J. Biol. Chem. 274, 14734-14742, (1999)


Selectively inhibits rat brain Ca2+/calmodulin-dependent protein kinase II.