Product: Calcium Folinate
Catalog Number: 17397
CAS Number: 6035-45-6
Synonyms: Folinic acid calcium salt hydrate; 5-Fromyl-5,6,7,8-tetrahydropteroyl-L-glutamic;
Leucovorincalcium salt; 5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt;
Citrovorum factorcalcium salt
5 mg =  Inquire  
50 mg =  Inquire  
Formula: C20H21CaN7O7 • xH2O
Chemical Purity: >99%
Molecular Weight: 511.50
Structure: Calcium Folinate
Appearance: Solid
Category: Anti-cancer compounds
Stability: Stable under recommended storage conditions.

Keep container tightly closed in a dry and well-ventilated place. Hygroscopic, store under inert gas. Light and air sensitive.


Non-hazardous for transport

Literature References:

L.O. Pont et al. Anal. Profiles Drug Subst. 8, 315, (1979)


Calcium folinate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.