Product: | Fotemustine | |
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Catalog Number: | 17496 | |
CAS Number: | 92118-27-9 | |
Pricing: |
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Formula: | C9H19ClN3O5P | |
Chemical Purity: | >98% | |
Molecular Weight: | 315.69 | |
Structure: | ||
Appearance: | Solid | |
Category: | Anti-cancer compounds | |
Stability: | Stable under recommended storage conditions | |
Storage: |
Keep container tightly closed in a dry and well-ventilated place |
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Transportation: |
Non-hazardous for transport |
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Literature References: |
Naumann, S.C., et al., Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. Br. J. Cancer 100, 322-333, (2009); Merle, P., et al., Chemotherapy-induced bystander effect in response to several chloroethylnitrosoureas: an origin independent of DNA damage? Anticancer Res. 28, 21-27, (2008); Ristic-Fira, A.M., et al., Effects of fotemustine or dacarbasine on a melanoma cell line pretreated with therapeutic proton irradiation. J. Exp. Clin. Cancer Res 28, 50, (2009); Merck 14,4261 |
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MSDS: | ||
Description: |
Fotemustine is a third generation nitrosourea, chloroethylating agent used in the treatment of glioma and malignant melanoma |