Product: | L-Thyroxine | ||||
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Catalog Number: | 18882 | ||||
CAS Number: | 51-48-9 | ||||
Synonyms: |
3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine; 3,3’,5,5”-Tetraiodo-L-thyronine; Levothyroxine |
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Pricing: |
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Formula: | C15H11I2NO4 | ||||
Chemical Purity: | 99% | ||||
Molecular Weight: | 776.87 | ||||
Structure: | |||||
Appearance: | Almost white to buff powder | ||||
Category: | Unlabeled Steroids and Hormones | ||||
Stability: | Stable under recommended storage conditions. | ||||
Storage: |
Keep container tightly closed in a dry and well-ventilated place |
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Transportation: |
Non-hazardous for transport |
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Literature References: |
Pastor, F.T., et al., Kinetic method for the determination of traces of thyroxine by its catalytic effect on the Mn(III) metaphosphate-As(III) reaction. Talanta 74, 1556-61, (2008); Tiefenbach, J., et al., A Live Zebrafish-based Screening System For Human Nuclear Receptor Ligand And Cofactor Discovery. PLoS ONE 5, e9797, (2010); Oppenheimer, J.H., et al., Advances in our understanding of thyroid hormone action at the cellular level. Endocr. Rev. 8, 288-308, (1987); DeGroot, L.J., and Niepomniszcze, H., Biosynthesis of thyroid hormone: basic and clinical aspects. Metabolism 26, 665-718, (1977); Dussault, J.H., and Ruel, J., Thyroid hormones and brain development. Annu. Rev. Pharmacol. Toxicol. 49, 321-334, (1987); Evans, R.M., The steroid and thyroid hormone receptor superfamily. Science 240, 889-895, (1988); Merck 14,9415; Beil. 14,IV,2373; Aldrich MSDS 1, 1709:B / Corp MSDS 1 (2), 3349:B / FT-IR 1 (2), 254:B / FT-IR 2 (2), 2749:A / RegBook 1 (2), 1845:F / Sigma FT-IR 1 (1), 724:B / Structure Index 1, 296:B:1 |
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MSDS: | |||||
Description: |
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis. |