Inquire About a Product| Product: | Chlortetracycline HCl | ||||||||
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| Catalog Number: | 4918 | ||||||||
| CAS Number: | 64-72-2 | ||||||||
| Synonyms: | Chlorotetracycline HCl | ||||||||
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| Chemical Purity: | 97% | ||||||||
| Molecular Weight: | 515.34 | ||||||||
| Structure: |
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| Category: | Unlabeled Reference Standards | ||||||||
| Literature References: |
Cerella, C., et al., Analysis of calcium changes in endoplasmic reticulum during apoptosis by the fluorescent indicator chlortetracycline. Ann. N.Y. Acad. Sci. 1099, 490-493, (2007); Agwuh, K.N., and MacGowan, A., Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines. J. Antimicrob. Chemother. 58, 256-265, (2006); Gillan, L., et al., Flow cytometric evaluation of sperm parameters in relation to fertility potential. Theriogenology 63, 445-457, (2005); Oliver, A.E., et al., Effects of temperature on calcium-sensitive fluorescent probes. Biophys. J. 78, 2116-2126, (2000); G. Schwartzman et al. Analytical Profiles of Drug Substances New York , (1979) 8, 101; Merck 14,2192; Beil. 14,IV,2631; Corp MSDS 1 (1), 871:B /RegBook 1 (2), 2097:N / Sax 6, 786 / Sigma FT-IR 1 (1), 637:A / Structure Index 1, 332:D:1 |
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| MSDS: | |||||||||
| Description: | Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline. Mode of Resistance: Loss of cell wall permeability | ||||||||
| Applications: | Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ |