Product: 7α-Hydroxy-4-cholesten-3-one-d7
Catalog Number: D10705
Unlabeled CAS Number: 3862-25-7
0.5 mg =  $890   Add to Cart
Formula: C27H37D7O2
Molecular Weight: 407.68
Structure: 7α-Hydroxy-4-cholesten-3-one-d<sub>7</sub>
Appearance: White solid
Category: Labeled Steroids & Hormones
Stability: Stable under recommended storage conditions.

Keep container tightly closed in a dry and well-ventilated place. Store at -20°C


Non-hazardous for transport

Literature References:

Gälman, C; Angelin, B; Rudling, M., Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis. Gastroenterology, 2005, 129 (5): 1445–53.; Russell, DW, The enzymes, regulation, and genetics of bile acid synthesis. Annual review of biochemistry, 2003, 72: 137–74.; Brydon, WG; Nyhlin, H; Eastwood, MA; Merrick, MV, Serum 7 α-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea. European journal of gastroenterology & hepatology, 1996, 8 (2): 117–23.

Applications: A labeled intermediate in the synthesis of bile acids from cholesterol. Serum concentrations reflect the activity of bile acid synthetic pathway. Elevated values suggest bile acid malabsorption.