Inquire About a Product| Product: | 25-Hydroxy cholesterol-26,26,26,27,27,27-d6 | ||||||||
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| Catalog Number: | D17191 | ||||||||
| CAS Number: | 88247-69-2 | ||||||||
| Synonyms: | 5-Cholesten-3β,25-diol-26,26,26,27,27,27-d6 | ||||||||
| Pricing: |
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| Formula: | C27H40D6O2 | ||||||||
| Enrichment: | 99 atom % d6 | ||||||||
| Chemical Purity: | >99% | ||||||||
| Molecular Weight: | 408.69 | ||||||||
| Structure: |
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| Appearance: | White solid | ||||||||
| Category: | Cholesterol | ||||||||
| Stability: | Stable under recommended storage conditions. | ||||||||
| Storage: |
Store at 2 - 8 deg. C |
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| Transportation: |
Non-hazardous for transport |
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| Literature References: |
Adams, C.M., Reits, J., De Brabander, J.K., Feramisco, J.D., Li, L., Brown, M.S., Goldstein, J.L., Cholesterol and 25-hydroxycholesterol Inhibit Activation of SREBPs by Different Mecanisms, Both Involving SCAP and Insigs. J. Biol. Chem., 2004, 279(50):52772-52780. |
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| MSDS: | |||||||||
| Description: | 25-hydroxy Cholesterol contains six deuterium atoms at the 26, 26, 26, 27, 27, and 27 positions. It is intended for use as an internal standard for the quantification of 25-hydroxy cholesterol by GC- or LC-mass spectrometry. | ||||||||
| Applications: | A labeled cholesterol derivative. Inhibits cholesterol synthesis. Suppresses the cleavage of sterol regulatory element binding proteins (SREBPs) in various cell types. Induces apoptosis. |