Product: 25-Hydroxy cholesterol-26,26,26,27,27,27-d6
Catalog Number: D17191
CAS Number: 88247-69-2
Synonyms: 5-Cholesten-3β,25-diol-26,26,26,27,27,27-d6
10 mg =  $210   (In Stock) Add to Cart
50 mg =  $695   (In Stock) Add to Cart
Formula: C27H40D6O2
Enrichment: 99 atom % d6
Chemical Purity: >99%
Molecular Weight: 408.69
Structure: 25-Hydroxy cholesterol-26,26,26,27,27,27-d<sub>6</sub>
Appearance: White solid
Category: Cholesterol
Stability: Stable under recommended storage conditions.

Store at 2 - 8 deg. C


Non-hazardous for transport

Literature References:

Adams, C.M., Reits, J., De Brabander, J.K., Feramisco, J.D., Li, L., Brown, M.S., Goldstein, J.L., Cholesterol and 25-hydroxycholesterol Inhibit Activation of SREBPs by Different Mecanisms, Both Involving SCAP and Insigs. J. Biol. Chem., 2004, 279(50):52772-52780.

Description: 25-hydroxy Cholesterol contains six deuterium atoms at the 26, 26, 26, 27, 27, and 27 positions. It is intended for use as an internal standard for the quantification of 25-hydroxy cholesterol by GC- or LC-mass spectrometry.
Applications: A labeled cholesterol derivative. Inhibits cholesterol synthesis. Suppresses the cleavage of sterol regulatory element binding proteins (SREBPs) in various cell types. Induces apoptosis.