Product: | 2,3-Pyridinedicarboxylic acid-d3 | ||||||||
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Catalog Number: | D18880 | ||||||||
Unlabeled CAS Number: | 89-00-9 | ||||||||
CAS Number: | 138946-42-6 | ||||||||
Synonyms: | Quinolinic Acid-d3 | ||||||||
Pricing: |
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Formula: | C7H2D3NO4 | ||||||||
Molecular Weight: | 170.14 | ||||||||
Structure: | |||||||||
Category: | Heterocyclic Compounds | ||||||||
Literature References: |
Guillemin, Gilles J., Quinolinic acid: neurotoxicity. FEBS Journal, 2012, March, 279(8): 1355.; Guillemin, Giles, Quinolinic acid, the inescapable neurotoxin. FEBS Journal, 2012, April, 279 (8): 1356–1365.; Tan, Lin; Yu, JT; Tan, L., The kynurenine pathway in neurodegenerative diseases: Mechanistic and therapeutic considerations. Journal of the Neurological Sciences, 2012, Dec., 323 (1–2): 1–8. |
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MSDS: | |||||||||
Applications: | A labeled NMDA receptor agonist. Inhibits glucose synthesis. Has potent neurotoxic effects. May be involved in many psychiatric disorders. Increased levels in the brain may contribute to apoptosis of astrocytes and neurons. |