Product: 1α,25-Dihydroxy vitamin D3-26,26,26,27,27,27-d6
Catalog Number: D3222
Unlabeled CAS Number: 32222-06-3
CAS Number: 78782-99-7
Synonyms: Calcitriol-26,26,26,27,27,27-d6;
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Formula: C27D6H38O3
Molecular Weight: 422.33
Structure: 1α,25-Dihydroxy vitamin D3-26,26,26,27,27,27-d<sub>6</sub>
Appearance: White Solid
Category: Vitamin D3
Stability: Stable if stored as directed

Long term storage: Stable if stored at -20°C in a tightly closed container.

Literature References:

D.J. Mangelsdorf et al; 1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells. J. Cell. Biol., 1984, 98, 391.; S.J. Slater et al; Direct activation of protein kinase C by 1 α,25-dihydroxyvitamin D3; J. Biol. Chem., 1995, 270, 6639.

Applications: 1alpha,25-Dihydroxy Vitamin D3 (26,26,26,27,27,27-d6) is the labeled, active hormonal form of vitamin D. It is one of the central regulators of bone and calcium homeostasis. It is also known to inhibit proliferation and induce differentiation of a wide range of cells as well as activate signal transduction pathways.