Product: | Cyclophosphamide-d4 | ||||
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Catalog Number: | D665 | ||||
CAS Number: | 173547-45-0 | ||||
Pricing: |
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Enrichment: | 99%D | ||||
Chemical Purity: | 98% | ||||
Molecular Weight: | 265.11 | ||||
Structure: | |||||
Appearance: | White to Off-White Solid | ||||
Category: | Labeled Reference Standards | ||||
Stability: | Stable under recommended storage conditions. | ||||
Storage: |
Keep tightly closed. Handle & store under nitrogen. Moisture sensitive. Freeze, avoid repeated exposure. Keep away from combustible materials, heat sparks & open flame. Wash thoroughly after handling. Do not breathe vapor. Longterm storage temperature: -20°C |
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Transportation: |
IATA: UN Number: UN3464; Hazard Class: 6.1; Packing Group: III; Shipping Name: Toxic Solid, Organic, N.O.S. (Cyclophosphamide) |
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Literature References: |
Huttunen KM, Raunio H, Rautio J., Prodrugs--from serendipity to rational design. Pharmacological Reviews, 2011, Sep., 63 (3): 750–71.; Shanafelt TD, Lin T, Geyer SM et al., Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia. Cancer, 2007, June, 109 (11): 2291–8.; Steinberg AD, Kaltreider HB, Staples PJ, Goetzl EJ, Talal N, Decker JL, Cyclophosphamide in lupus nephritis: a controlled trial. Annals of Internal Medicine, 1971, Aug., 75(2): 165–71. |
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MSDS: | |||||
Applications: | A labeled nitrogen mustard alkylating agent. Attaches an alkyl group to the guanine base of DNA, which interferes with DNA replication. Used to treat cancers, autoimmune disorders, and AL amyloidosis. |